Helen He Zhu is currently a principal investigator and professor at the State Key Laboratory of Systems Medicine for Cancer and Renji Hospital, School of Medicine, Shanghai, China. Dr. Helen He Zhu obtained her Bachelor Degree from Fudan University, China. She received her Ph.D. training at the School of Medicine, University of California-San Diego and performed her postdoctoral research at the Department of Biology, University of California-San Diego. In 2012, Dr. Zhu moved back to China and joined Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University as an associate professor and then professor. Her current work focuses on 1) adult tissue stem cells from hematopoietic system and prostate in tissue development and tumorigenesis, 2) tumor microenvironment with a focus on cancer-associated fibroblasts and nerves, and 3) development of novel targeted therapy for castration-resistant and metastatic prostate cancer. She was elected as Shanghai Excellent Academic Leader (2021) and National Excellent Young Scholar (2020). Prof. Helen He Zhu has served as a reviewer for several journals (e.g., Cell Stem Cell, Cell Reports, Advanced Science, EMBO molecular medicine.…) and grants in the past. She is now associate editor for Cellular Oncology.